Sleep Patch With Melatonin 3 Pack

Melatonin (chemically N-acetyl-5-methoxytryptamine) is a hormone produced mainly by the pineal gland in your brain in response to darkness; it helps regulate your sleep-wake (“circadian”) cycle. Because of its molecular structure, it’s able to cross cell membranes and reach many tissues. It acts via specific receptors (MT₁, MT₂) to signal to your body that it’s time to wind down, lower body temperature, reduce alertness, and prepare for sleep. It also has antioxidant and anti-inflammatory properties: melatonin helps neutralize free radicals, supports antioxidant enzymes, and may protect cells from damage.

Valerian extract, derived from the roots of Valeriana officinalis, is best known for its calming, sleep-inducing, and anxiety-modulating effects. Its active compounds—especially valerenic acid, valerenol, valepotriates, flavonoids, and volatile oils—interact with the brain’s GABA receptors (which promote relaxation), and may also influence serotonin and adenosine pathways. People using standardized extracts (≈ 300-600 mg) report improvements in how fast they fall asleep, better sleep quality, and reduced nighttime awakenings. It also shows potential for easing stress, anxiety, and nervous tension. Mild side effects (like drowsiness, headache, stomach upset) are possible, and long-term safety is less well established.

Passion flower (Passiflora incarnata) extract comes from the flowers, leaves, and stems of the plant. Its main bioactive constituents include flavonoids (such as apigenin, luteolin, vitexin, isovitexin, orientin, iso-orientin, quercetin, kaempferol), indole alkaloids (like harman, harmine, harmaline), glycosides (e.g. passiflorine), maltol, and other phenolic compounds. These compounds work together to produce anxiolytic (anxiety-reducing), sedative, and calming effects. One of the main ways it works is by interacting with the GABAergic system in the brain, which helps reduce neuronal overactivity and promotes relaxation and better sleep. Clinical and non-interventional studies show improvements in sleep quality, reduced nervous restlessness, anxiety, and boosted quality of life when taken for several weeks.

Hops extract is derived from the flowers (cones) of Humulus lupulus. It contains bitter resins (alpha-acids like humulones and beta-acids like lupulones), flavonoids (such as xanthohumol, 8-prenyl-naringenin), essential/volatile oils (e.g. humulene, myrcene, caryophyllene), phenolic acids, tannins, and other compounds. These constituents contribute to its sedative/calming effects (via some action on the GABA system), antioxidant, anti-inflammatory, antimicrobial effects, and even mild estrogen-like activity (useful in certain hormonal contexts). MedicineNet It’s often used for insomnia, anxiety, restlessness, digestibility, menopausal symptoms, and to reduce nervousness.