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Valerian extract, derived from the roots of Valeriana officinalis, is best known for its calming, sleep-inducing, and anxiety-modulating effects. Its active compounds—especially valerenic acid, valerenol, valepotriates, flavonoids, and volatile oils—interact with the brain’s GABA receptors (which promote relaxation), and may also influence serotonin and adenosine pathways. People using standardized extracts (≈ 300-600 mg) report improvements in how fast they fall asleep, better sleep quality, and reduced nighttime awakenings. It also shows potential for easing stress, anxiety, and nervous tension.

Passion flower (Passiflora incarnata) extract comes from the flowers, leaves, and stems of the plant. Its main bioactive constituents include flavonoids (such as apigenin, luteolin, vitexin, isovitexin, orientin, iso-orientin, quercetin, kaempferol), indole alkaloids (like harman, harmine, harmaline), glycosides (e.g. passiflorine), maltol, and other phenolic compounds. These compounds work together to produce anxiolytic (anxiety-reducing), sedative, and calming effects

Hops extract is derived from the flowers (cones) of Humulus lupulus. It contains bitter resins (alpha-acids like humulones and beta-acids like lupulones), flavonoids (such as xanthohumol, 8-prenyl-naringenin), essential/volatile oils (e.g. humulene, myrcene, caryophyllene), phenolic acids, tannins, and other compounds. These constituents contribute to its sedative/calming effects (via some action on the GABA system), antioxidant, anti-inflammatory, antimicrobial effects, and even mild estrogen-like activity (useful in certain hormonal contexts).